Small molecules are central players as ... of macromolecular structural biology on all levels. Determining structures of large molecular assemblies by methods including crystallography, electron ...

Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level. The ...

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

Scientists in Japan have uncovered a surprising twist, literally, in how molecules organize themselves. By introducing tiny leftover fragments from previous assemblies, they discovered a way to flip ...