Centrioles, organelles that organize the microtubule spindle required for cell division, duplicate at almost exactly the same time that DNA replicates during the cell cycle. New research points to ...

TEDC1 and TEDC2, functions in generating centriolar triplet microtubules, and that this is crucial for the proper formation of centriolar subdomains and the stability of centrioles throughout the cell ...

The centrioles are now at opposite ends of the cell. The spindle fibers from both of the centrioles attach to each one of the chromosomes. Same as in mitosis, except that the spindle fibers from ...

Two recent studies in Drosophila demonstrate that overexpression of proteins required for centriole duplication can not only induce centriole over-duplication in cells containing centrioles ...

This is especially true near the center of the cell, the location of the centrioles near the nucleus. This is a great time to introduce the three categories of cytoskeletal components: microfilaments, ...

These centrosomes, composed of centrioles surrounded by a protein-dense matrix, act as hubs for cell cycle regulators. In organisms like yeast, spindle pole bodies (SPBs) function similarly but ...

The goal of my research is to understand the biogenesis of centrioles/centrosomes and primary cilia, and how defects in these processes affect mammalian cell physiology and evoke stress responses.

Each copy is called a chromatid. A spindle begins to form from the centrioles. This spindle is made of fibers. The centrioles begin to separate. The activities are the same as in mitosis ...