In this study, a screening was carried out utilizing patient-derived 3D spheroids (tumoroids). In addition to readouts on cell viability, the Cell Painting assay was adapted for the 3D tumor model.

More information: Yanli Wang et al, Reconstructing 3D chromosome structures from single-cell Hi-C data with SO (3)-equivariant graph neural networks, NAR Genomics and Bioinformatics (2025).

Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model. Nature Neuroscience, 2023; DOI: 10.1038/s41593-023-01415-3 ...

A novel 3D human cellular model Cognitive decline associated with Alzheimer’s disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive ...

Their research, published May 28 in Cell Reports Methods, uses this mouse model to show how two types of stem cells in the nose, called horizontal basal cells (HBCs) and globose basal cells (GBCs ...

As described in research published today in Cell, the new model can be used to study the origin and function of the human amnion and help identify previously unknown ways the amniotic sac might ...

For the recent study, the researchers performed a biopsy to collect stem cells from the testicles of a patient living with NOA. The cells were then grown and 3D printed onto a petri dish into a hollow ...

The claim: Photo shows the most detailed model of human cell to date A colorful, intricate diagram circulating on social media is being presented as a groundbreaking picture of a human cell. "This ...

Existing three-dimensional (3D) neuronal culture technology has limitations in brain research due to the difficulty of precisely replicating the brain's complex multilayered structure and the lack of ...

New AI tool reveals single-cell structure of chromosomes — in 3D A breakthrough at the University of Missouri could help scientists better understand how genes work — and how certain types of ...