With its selection of kits (cAMP femto, cAMP dynamic and cAMP HiRange ... this causes the exchange of GDP bound to Gα for GTP, followed by the dissociation of Gα-GTP from the complex.

The GTP-bound α-subunit is then thought to dissociate ... As Janetopoulos and colleagues found that sustained exposure to cAMP leads to a prolonged loss of the FRET fluorescence signal, the ...