Because cancer cells have a lot of P-cadherin sticking out of their surface, the protein has been targeted for drug development. Monoclonal antibodies against P-cadherin can carry a drug payload ...

Assessment of cadherin-11 as a therapeutic target was also performed in mice with established arthritis, and administration of a monoclonal antibody towards cadherin-11 ameliorated the arthritis.

a novel antibody-drug conjugate (ADC) targeting cadherin-17 (CDH17). The data highlight SOT109's promising activity and tolerability profile across multiple disease models, reinforcing its ...

Through comparative transcriptome analysis, Professor Kai-Chien Yang's group identified the adherens junction protein N-Cadherin as a key regulator of CM proliferation and renewal. Its expression ...