Huo Xue Tong Luo Capsule (HXTL) has been clinically used to treat osteonecrosis of the femoral head, osteoporosis, and other bone and joint diseases with promising effects.

Based on these findings, the team examined whether the Notch signaling pathway controls SSPC differentiation ... the team found upregulation of bone formation genes which might prime the SSPC for ...

has recently been developed that acts on the cGMP signaling pathway in bone and is used to treat dwarfism in children. The parallels that our study has shown between bone growth and the formation ...

Huo Xue Tong Luo Capsule (HXTL) has been clinically used to treat osteonecrosis of the femoral head, osteoporosis, and other bone and joint diseases ...

The Wnt/β-catenin signaling pathway plays an important role in bone formation. Signaling is initiated by the binding of Wnt to a Frizzled receptor as well as a low-density lipoprotein receptor ...

Sclerosteosis is a rare genetic disorder that causes excessive bone growth, leading to life-altering complications, including hearing loss and facial paralysis.

A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular ...

signaling in the pathogenesis of OPLL, particularly the type I IFN pathway, which is known to play a role in innate immune responses and bone formation. A single-cell transcriptome profiling study ...

A landmark review in Nature Reviews Genetics dissects the rare and common genetic variants that shape human height. The paper explains how monogenic and polygenic factors converge on key growth ...