Furthermore, the scientists discovered that two other key Alzheimer’s-disease-related proteins, beta-secretase and presenilin-1, are found together with APP inside the packet. Beta-secretase and ...

The organisations have ended development of the BACE1 (beta secretase 1) inhibitor CNP520 – or umibecestat – which was in two phase 2/3 studies in the Alzheimer's Prevention Initiative ...

For this, they examined the expression of the genes BACE1 and APP, which code for beta-secretase component 1 and amyloid precursor protein, respectively, and the MBP gene, which codes for myelin ...