Researchers have developed the first comprehensive atlas of allele-specific DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation. The study identified ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA methylation across 39 primary human cell types.The study was led by Ph.D ...

DNA methylation ... methylation levels and completeness of methylation of particular promoters are similar in individual humans, there are significant differences in overall and specific ...

DNA methylation is a key factor in the regulation of organismal development and tissue homeostasis. DNA methylation marks indicate how to regulate ...

By analyzing vast troves of genetic and phenotypic data at a population scale, researchers can identify important associations between genetic variants and specific traits ... 11 Though its effects ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

DNA methylation is a fundamental epigenetic mechanism ... targeted bisulfite sequencing allows researchers to investigate the methylation status of each cytosine in a specific genomic region.

a phenomenon known as allele-specific methylation. Some of these methylation changes are caused by genetic differences in genomic sequence of DNA, while others are due to parental imprinting—a ...