Researchers have developed the first comprehensive atlas of allele-specific DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation. The study identified ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA methylation across 39 primary human cell types.The study was led by Ph.D ...

DNA methylation ... methylation levels and completeness of methylation of particular promoters are similar in individual humans, there are significant differences in overall and specific ...

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types ... dimensional structure of the genome and DNA ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

DNA methylation is a fundamental epigenetic mechanism ... targeted bisulfite sequencing allows researchers to investigate the methylation status of each cytosine in a specific genomic region.

a phenomenon known as allele-specific methylation. Some of these methylation changes are caused by genetic differences in genomic sequence of DNA, while others are due to parental imprinting—a ...