and the presence of specific amino acid residues. Hydrolysis, or peptide bond cleavage via reaction with water, is theorized to be a primary degradation mechanism, particularly in aqueous solutions.

Within a protein, multiple amino acids are linked together by peptide bonds, thereby forming a long chain. Peptide bonds are formed by a biochemical reaction that extracts a water molecule as it ...

Peptide bonds are formed between a carbon atom from one amino acid and a nitrogen atom of ... which are still susceptible to hydrolysis. "Collagen is all triple helices, from one end to the ...

Proteases are enzymes that catalyse hydrolysis of the peptide and isopeptide bonds that join amino acids within proteins (known as proteolysis). Proteases can also remove protein post ...

Lyophilization (freeze-drying) is commonly utilized to support peptide stability. Removing water from peptide solutions might significantly reduce hydrolysis and deamidation rates. Lyophilized ...