We examined the influence of rapacuronium on acetylcholine (ACh) binding to and activation of individual subtypes of muscarinic receptors expressed in Chinese hamster ovary cells to determine its ...

She further showed that lynx1 had a dramatic effect on enhancing desensitization of the receptors to acetylcholine, and it did so by directly binding to the receptors,” he said. Co-author Steven Sine ...

The pharmacotherapy of schizophrenia is currently dominated by atypical antipsychotics that primarily target dopaminergic signalling, the dysregulation of which has long been considered to have a ...

acetylcholine binding to dopamine axons was impaired, leading to less calcium influx. Increasing calcium restored dopamine release, showing that the problem lies in nicotinic receptor function.

Its products includes cytisine, a plant-based alkaloid with a binding affinity to the nicotinic acetylcholine receptor. The company was founded in October 1991 and is headquartered in Vancouver ...