NEW YORK — Rookie Marcelo Mayer is not in Boston’s lineup Saturday against a left-handed starting pitcher. The Red Sox and Yankees will play the second game of their three-game series at 7:35 p.m. here at Yankee Stadium. It will be aired nationally on FOX.

The New York Yankees will face off against the Boston Red Sox in an MLB matchup on Saturday. This prediction features our best bet of the game.

The Boston Red Sox (30-35) and New York Yankees (39-23) play the second game of their 3-game series Saturday. First pitch from Yankee Stadium is set for 7:35 p.m. ET (MLB Network). Let's analyze BetMGM Sportsbook's MLB odds around the Red Sox vs. Yankees odds and make our expert MLB picks and predictions for the best bets.