Pythagoreio is a town and municipal unit on the island of Samos, North Aegean, Greece. Before the 2011 local government reform, Pythagoreio was a municipality. Since 2019, it is a municipal unit of East Samos. In 2021, the town's population was 7,515. It is the largest municipal unit in land area on Samos, at 164.662 km. It shares the island with the mu…Pythagoreio is a town and municipal unit on the island of Samos, North Aegean, Greece. Before the 2011 local government reform, Pythagoreio was a municipality. Since 2019, it is a municipal unit of East Samos. In 2021, the town's population was 7,515. It is the largest municipal unit in land area on Samos, at 164.662 km. It shares the island with the municipal units of Vathy, Karlovasi, and Marathokampos. The archaeological remains in the town, known collectively as Pythagoreion, has designated a joint UNESCO World Heritage Site with nearby Heraion.